P03-019 - Anakinra for sweet syndrome treatment
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چکیده
منابع مشابه
P03-019 - Anakinra for sweet syndrome treatment
Case report 1A 72-year-old man with diagnosis of Relapsing Polychondritis and Myelodysplastic syndrome (MDS) was referred for a 4-yr history of recurrent fever (37.5 to 39°C) accompanied by sudden onset of cutaneous purple papules on the extremities and hypodermic painful nodules on the forehead and scalp. The patient suffered of autoimmune atrophic gastritis and severe metasteroidal osteoporos...
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Methods We retrospectively reviewed the charts of all BS patients evaluated with a suspicion of gastrointestinal involvement. We identified those with GIBS and surveyed their demographic features, other BS manifestations, clinical, endoscopic and histologic gastrointestinal findings, and treatment modalities. Patients were evaluated either in the outpatient clinic or if not possible by phone ca...
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Osteoarthritis (OA) is the most common form of arthritis and one of the leading causes of disability worldwide. The incidence of OA increases with age, and as longevity increases, it will cause a significant socioeconomic burden. No disease-modifying therapy is available for OA. Recent research has highlighted the role of inflammation in the progression of OA. Interleukin-1 appears to have a si...
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Schnitzler syndrome is a rare acquired systemic disease with a chronic evolution and difficult treatment. We report a 50-year-old woman with Schnitzler syndrome for 10 years, with major impact on her quality of life and refractory to conventional therapies. The patient was started on anakinra, an IL-1 receptor antagonist, with a rapid and sustained remission of the syndrome manifestations.
متن کاملInterleukin-1 receptor antagonist (anakinra) for Schnitzler syndrome.
Schnitzler syndrome is a rare autoinflammatory disease, which is defined by the presence of two major criteria: chronic urticaria and monoclonal immunoglobulin M (IgM) or immunoglobulin G gammopathy, in combination with at least two additional minor criteria: recurrent fever, leukocytosis and/or elevated C-reactive protein (CRP), objective signs of abnormal bone remodelling and a neutrophilic i...
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ژورنال
عنوان ژورنال: Pediatric Rheumatology
سال: 2013
ISSN: 1546-0096
DOI: 10.1186/1546-0096-11-s1-a217